ALP fermenter retrofit (pharma)

Basic and detailed design for a fermenter retrofit in a pharmaceutical plant.

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Fermenter retrofit

Project summary

SectorPharma & biotechCompanyNovo Nordisk
LocationMontes Claros – MGApproximate investmentUS$ 30 million
Project no.OS 037Scope
  • Basic and detailed design
  • Fermenter retrofit
  • Installation of a new centrifuge
  • Clean utilities and black utilities

The main challenge

Engecell worked on the basic and detailed design.

The fermentation was reworked without invasive changes to the main equipment, making the process more stable and less prone to contamination. The technology was preserved, keeping the worldwide production strategy for the stages of the process that makes insulin for human use.

Key success indicators

The design was audited and defended in a workshop with the contractor and the end client
The end client involved its production, engineering and research teams and approved the final design with few comments

Engecell's challenges

Using 3D software more competitive than the ones used on large greenfield projects
Meeting every pharmaceutical requirement

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